.png)
PRODUCT DETAILS
Product specifications
The human 26S immunoproteasome is a native, ATP-dependent multiprotein protease composed of a 20S immunoproteasome core associated with one or two 19S regulatory particles. Its catalytic core is enriched in the immunoproteasome subunits β1i/LMP2, β2i/MECL-1 and β5i/LMP7, which distinguish it from the constitutive 26S proteasome and alter its proteolytic cleavage preferences. The complex participates in regulated intracellular protein degradation and the generation of peptides for MHC class I antigen presentation.
Our 26S immunoproteasome is isolated directly from human spleen tissue by fractionation, without recombinant expression or affinity tags, preserving the complex in its native state.
SOURCE
Purified by fractionation from human spleen tissue.
Highly active, soluble, and homogeneous
FORMULATION
Liquid.
In 20mM Tris-HCl, 25mM KCl, 1.1mM MgCl₂, 0.1mM EDTA,
1mM DTT, 1mM sodium azide, 2mM ATP, pH 7.0, and 35% glycerol
Buffer ingredients can be adjusted to customer needs
SHIPPING
Shipped on dry ice
LONG-TERM STORAGE
Store at −80°C. Avoid repeated freeze/thaw cycles
PACKAGE
50 μg standard one unit quantity.
Contact us for larger quantities and custom requirements
UNIT PRICE
390 $ USD per 50 μg unit