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PRODUCT DETAILS
Product specifications
The eukaryotic proteasome contains 7α-type and 7 β-type subunits. Upon stimulation with IFN-γ, the three active β subunits, β1 (Y), β2 (Z), and β5 (X), are exchanged for their immunocounterparts, namely β1i (LMP-2), β2i (MECL-1), and β5i (LMP-7). This results in a change in proteasomal substrate specificity. Some groups have reported increases in chymotrypsin-like and trypsin-like activities, while others have reported no changes or even decreased activities after such treatment.
SOURCE
Purified by fractionation from human white blood cells.
Highly active, soluble, and homogeneous
FORMULATION
Liquid.
In 20mM Tris-HCl, 1mM sodium azide, 1mM DTT, pH 7.2.
Contains 50% glycerol.
Buffer ingredients can be adjusted to customer needs
SHIPPING
Shipped on dry ice
LONG-TERM STORAGE
Store at −80°C. Avoid repeated freeze/thaw cycles
PACKAGE
50 μg standard one unit quantity.
Contact us for larger quantities and custom requirements
UNIT PRICE
350 $ USD per 50 μg unit